Cardiovascular

<p>Cardio Care, provides five key complementary compounds with an established evidence base for their lipid-supportive properties. These nutrients, which include red yeast rice extract, phytosterols, garlic, berberine, and delta-tocopherol, provide support for healthy lipid metabolism and cardiovascular health.</p> <p>In addition, the ingredients in Cardio Care have been shown to modulate the body’s natural inflammatory response as well as healthy blood pressure, arteries, and coronary artery calcium scores. The natural ingredients in Cardio Care are very well-tolerated, and in clinical trials, have generally enhanced the effects of other lipid-supportive agents.</p> <p> </p> <p>*Compare to Cardio-Lipid</p> <!---->

<meta charset="UTF-8"> <div data-mce-fragment="1">Lions Mane Complex is a blend of Lion's Mane and Cordyceps that provides both mental and physical benefits. Blended in combination with Gotu Kola and Siberian Ginseng leading to superior results.</div> <div data-mce-fragment="1"><br data-mce-fragment="1"></div> <div data-mce-fragment="1">Up-level your mental clarity and cognitive support, with tranquility. Crafted with precision, this non-alcohol-based tincture combines the power of Lion's Mane mushroom with a synergistic herbal partner, Organic Gotu Kola.</div> <div data-mce-fragment="1"><br data-mce-fragment="1"></div> <div data-mce-fragment="1">Synergistic Herbal Pairing: The partnership between Lion's Mane and Organic Gotu Kola is a harmonious fusion of natural wisdom. This powerful combination aims to nourish your brain, helping you stay sharp &amp; focused.<br data-mce-fragment="1"> </div> <div data-mce-fragment="1"> <br data-mce-fragment="1">Potential Benefits of Lion's Mane Tincture with Organic Gotu Kola:<br data-mce-fragment="1"><br data-mce-fragment="1">Enhanced Cognitive Function: Lion's Mane is renowned for its potential to support mental clarity &amp; focus. Organic Gotu Kola is a powerful ally for boosting cognitive function &amp; improving memory retention.<br data-mce-fragment="1"><br data-mce-fragment="1">Neurological Support: research suggests that Lion's Mane may have neuroprotective properties. The combination with Gotu Kola further supports overall brain health and promotes a healthy nervous system.<br data-mce-fragment="1"><br data-mce-fragment="1">Stress Reduction: Both Lion's Mane and Gotu Kola have traditionally been used to combat stress and promote a sense of calm.<br data-mce-fragment="1"> </div> <div data-mce-fragment="1"><br data-mce-fragment="1"></div> <span data-mce-fragment="1">Enhance your performance with a natural energy booster. Crafted with precision, this non-alcohol-based tincture combines the power of Cordyceps militaris mushroom with a synergistic herbal partner, Organic Siberian Ginseng.</span> <div data-mce-fragment="1"><br data-mce-fragment="1"></div> <div data-mce-fragment="1">Synergistic Herbal Pairing: To amplify the energizing effects of Cordyceps militaris, we've paired it with Siberian Ginseng, a renowned herb. This dynamic combination supports your body's resilience to stress and promotes sustained energy throughout the day.<br data-mce-fragment="1"><br data-mce-fragment="1">Potential Benefits of Cordyceps Tincture with Siberian Ginseng:<br data-mce-fragment="1"><br data-mce-fragment="1">Increased Stamina and Energy: Cordyceps militaris is known for its ability to enhance physical endurance and improve energy levels. Combined with Siberian Ginseng, our tincture becomes a natural energy booster, helping you power through your daily activities.<br data-mce-fragment="1"><br data-mce-fragment="1">Natural Support: Siberian Ginseng, an natural and homeostatic herb, works in synergy with Cordyceps militaris to support your body's response to stress, promoting a balanced and resilient state of well-being.<br data-mce-fragment="1"><br data-mce-fragment="1">Respiratory Health: Cordyceps militaris has been traditionally used to promote lung health and overall respiratory well-being.<br data-mce-fragment="1"><br data-mce-fragment="1">Ingredients:<br data-mce-fragment="1"><br data-mce-fragment="1">100% Fruiting Body Extracted Lion’s Mane Mushroom</div> <div data-mce-fragment="1"><br data-mce-fragment="1"></div> <div data-mce-fragment="1">100% Fruiting Body Extracted Cordyceps militaris Mushroom<br data-mce-fragment="1"><br data-mce-fragment="1">USDA Certified Organic Gotu Kola</div> <div data-mce-fragment="1"><br data-mce-fragment="1"></div> <div data-mce-fragment="1">USDA Certified Organic Siberian Ginseng <br data-mce-fragment="1"><br data-mce-fragment="1">Organic Vegetable Glycerin<br data-mce-fragment="1"><br data-mce-fragment="1">Distilled Water</div>

<p>Berberine is a plant alkaloid derived from several different plant species customarily used in Ayurveda and traditional Chinese medicine for various therapeutic applications. Modern clinical use and published in vivo, in vitro, and animal research studies<br>demonstrate that the berberine metabolite dihydroberberine (DHB) is more bioavailable than berberine and offers enhanced support for healthy blood glucose metabolism.<br></p> <p>Although the mechanisms underlying the beneficial effects of berberine are not entirely clear, it is hypothesized that the modulation of gut microbes may be one mechanism by which berberine affects blood glucose metabolism. Results from animal and in<br>vitro studies suggest that berberine moderates glucose and lipid metabolism through a multi-pathway mechanism, including the adenosine monophosphate–activated protein kinase (AMPK), c-Jun N-terminal kinase (JNK), and peroxisome proliferator-activated<br>receptor (PPAR)-alpha pathways. Separate research on AMPK reports activating the AMPK pathway stimulates glucose uptake and fat oxidation while suppressing lipogenesis and gluconeogenesis. Berberine is also believed to be involved in the regulation of pancreatic beta cell function, and it has been observed to inhibit the expression of disaccharidases in the duodenum, resulting in less glucose formation from carbohydrate digestion.<br></p> <p>Increasing evidence indicates that gut microbiota are also crucial mediators that regulate berberine’s pharmacokinetic and biological effects. Berberine induces compositional alterations in gut microbiota and regulates gut microbe–dependent metabolites, factors<br>that contribute to its biological effects on lipid and glucose metabolism. Additionally, gut microbiota reduce berberine to DHB, its intestine-absorbable form, which then oxidizes back to berberine after it has been absorbed into intestinal tissues and entered the blood.<br></p> <p>Berberine absorption across the intestinal epithelia is suggested to be compromised because of its “flat” chemical configuration. Berberine displays poor bioavailability and increased potential for GI distress at the oral doses required to improve biomarkers associated with glucose homeostasis. The structure of the DHB derivative of berberine is comparably open, making it more amenable to uptake. To further explore the absorbability of berberine and DHB, researchers investigated the mechanism of action by which AMPK is activated and if using DHB at lower doses than berberine could potentially improve the effect on adiposity and glucose metabolism in rodents fed a high-fat diet. Berberine had to be administered at a nearly 5-fold increased dose of 560 mg/kg/d to establish the same effects demonstrated by DHB at 100 mg/kg/d. The rodents treated with the substantially lower dose of DHB showed markedly reduced adiposity and improved glucose tolerance. Additionally, insulin sensitivity was increased in the DHB-treated animals. These results led researchers to suggest that the difference in effects between berberine and DHB is due to the enhanced bioavailability of DHB. The findings of this study indicate that DHB delivers the beneficial metabolic effects of berberine in a more absorbable form and at a lower dose.<br></p> <p>A small, randomized, double-blind, crossover pilot study (N = 5) investigated the absorption kinetics and compared the dosing of berberine and DHB required to achieve peak plasma concentrations. Subjects completed a 4-dose protocol of placebo, 500 mg of berberine, 200 mg of DHB, and 100 mg of DHB. Participants ingested the first 3 doses with breakfast, lunch, and dinner, followed by an overnight fast, then a standardized test meal accompanied by dose 4. Blood samples were collected at regular intervals after ingestion and analyzed for berberine, glucose, and insulin. Four doses of 100 mg and 200 mg of DHB produced significantly greater concentrations of plasma berberine across the 2-hour measurement window than a 500-mg dose of berberine or placebo.<br>Results suggest that irrespective of dose, DHB achieves a greater area under the curve and peak berberine concentrations when compared with oral ingestion of berberine.<br></p> <p>Keystone Compounding Pharmacy’s Berberine ES contains DHB originating from berberine sourced from Berberis aristata and naturally extracted through an enzymatic process similar to that which occurs in the human gut. With a 5-fold relative increase in<br>absorption rate, supplemental DHB at much lower doses than berberine has comparable beneficial metabolic effects.</p> <p><strong>Suggested Use:</strong></p> <p>1 capsule once or twice daily, or use as directed by your healthcare professional.</p>

<p>While a healthy diet and exercise are paramount to good health and maintaining healthy body composition, adding supplementary soluble fiber offers additional benefits. When selecting fiber, there are many aspects to review. Each fiber is unique in origin, purity, viscosity, and overall stability once ingested. In fact, even one type of fiber can vary greatly in quality. Amorphophallus konjac, a tuberous plant, is a rich source of the<br>soluble fiber glucomannan. This fiber has an exceptional ability to absorb water and is one of the most viscous dietary fibers known.<br></p> <p><strong>Not All Glucomannans Are Created Equal</strong><br>There are many aspects of glucomannan that affect end-product quality: the species of konjac used, the harvesting location, the time of harvesting, the production process, impurities (e.g., sulfites), viscosity, the response of the viscosity to different pH levels and temperatures, and hydration speed. For these reasons, finding the material with the most manufacturing and processing experience and scientific research behind it is important.<br></p> <p><strong>Propol® A Propolmannan</strong><br>Shimizu Chemical Corporation is a pioneer in the world of dietary fiber and its health benefits. Using its vast knowledge—over 300 years of processing raw material (Japanese Amorphorphallus konjac species) and extracting glucomannan—it has developed Propol A propolmannan, a highly purified glucomannan. Shimizu’s unique and proprietary three-stage purification process is carried out in large-scale extraction plants and involves pulverizing the Amorphophallus tubers, collecting mannan-glucose particles, and polishing the particles in order to dislodge and extract noxious materials that adhere to them. With the use of cutting-edge technology, Propol A has been reduced to a special particle size that maximizes density while remaining in desirable viscous form. This process yields a pure, refined, high-performance Amorphophallus propolmannan that improves product solubility, stability, and overall functionality.<br></p> <p><strong>Viscosity, Stability Through the Digestive Tract</strong><br>Viscosity is a physicochemical property of soluble fiber that reflects the fiber’s ability to thicken as it mixes with fluid. Viscosity is a recognized factor affecting physiological responses to soluble fiber. Propol A features an extremely high viscosity (100,000 mPa·s), which is thought to contribute to its health benefits. Furthermore, as a benefit of its unique processing, Propol A remains intact in the digestive tract—another key factor in fiber functionality. Viscosity and stability, taken together, produce a highly effective material that, once in the digestive tract, attracts water and forms a viscous gel-like substance that slows digestion, delays the emptying of food from the stomach into the small intestine, slows down the influx of carbohydrates and fats into the bloodstream, binds to bile acids, and impedes dietary fat absorption.<br></p> <p><strong>Satiety and Weight Control</strong><br>Soluble fiber is known to act as a bulking agent in the stomach and intestine, which creates the signals of fullness and causes individuals to eat less. Studies suggest that glucomannan supplementation significantly reduces weight at doses of 3 g/d to 4 g/d when compared to placebo. In a randomized, double-blind, placebo-controlled study, the effects of 3 g/d of Propol (1 g 30-60 minutes prior to each meal) combined with 300<br>mg/d of calcium were studied. When dosing compliant and non-complaint subgroups were analyzed, the results indicated that compliant subjects experienced a significant reduction in scale weight, body fat percentage, and fat mass without a loss of fat-free mass or bone density. In another study, the mean weight loss for the glucomannan group was 5.5 lbs in eight weeks, while subjects in the placebo group gained 1.5 lbs.<br></p> <p><strong>Glucose and Lipid Metabolism</strong><br>Soluble fiber slows the absorption of carbohydrates, which influences the release of insulin and the rate of fat storage. Glucomannan studies have not only demonstrated a positive impact on postprandial glucose handling and glucose metabolism but also on cholesterol metabolism. This latter effect is thought to result from the fact that soluble fiber reduces fat and cholesterol absorption and carries bile out of the intestines.<br>When fewer bile acids are available, the body draws cholesterol from the bloodstream to make more.<br></p> <p><strong>Healthy Bowel Function, Prebiotic</strong><br>Glucomannan not only allows more water to remain in the stool, thereby making waste softer, larger, and easier to pass through the intestines, but it is also an excellent prebiotic. In a placebo-controlled, randomized, parallel, double-blind, crossover trial, doses of 3 g/d and 4 g/d of glucomannan had a positive impact on intestinal habit (i.e., daily and weekly evacuations) and stool characteristics when compared to placebo.<br> Glucomannan has also been shown to reduce mouth-to-cecum transit time compared to placebo. In other research, glucomannan improved defecation frequency, eased bowel movement, increased the fecal concentration of lactobacilli as well as the daily output of bifidobacteria, lactobacilli, and total bacteria. In addition, fermentation of glucomannan resulted in greater fecal acetate, propionate, and i-butyrate concentrations<br>and lower fecal pH.</p> <p><strong>Directions:</strong></p> <p>Mix one to two scoops (1.6-3.2 g) in 8-12 oz of water or other non- alcoholic beverage and consume once per day, or mix one scoop as directed and consume 30 to 60 minutes before each of your two biggest meals, or use as directed by your healthcare professional.</p>

<p>New research is focusing on the synergistic relationship between vitamin K2 and vitamin D3, for bone and cardiovascular health. A group of naturally occurring and structurally similar, fat-soluble vitamins, vitamin K is essential for the proper utilization of calcium. Through its activation of the protein osteocalcin, vitamin K helps to bind newly absorbed calcium to the mineral matrix in bone. In addition, vitamin K has been found to help maintain bone mineral density by decreasing the activity of osteoclasts, a cell that breaks down the bone matrix. Vitamin K also provides critical cardiovascular protection by helping to activate matrix Gla protein (MGP), an inhibitor of circulatory calcification. Thus, vitamin K and vitamin D not only share similar qualities, but they also act synergistically within the body.</p> <p>The addition of<span> </span><strong>MenaQ7® PRO</strong><span> </span>to this formula is backed by extensive research. Dr. Leon Schurgers, world-renowned expert in vitamin K2 as MK-7 research for cardiovascular and bone health, and his team of research scientists have conducted over 15 clinical trials on MenaQ7® PRO through the University of Maastricht.</p> <p>Vitamin K2 with D3 includes 45 mcg of<span> </span><strong>MenaQ7® PRO</strong>, the most widely studied form of vitamin K2 as MK-7, and 5,000 IU of vitamin D3 per capsule for optimal absorption and use by the body.</p> <p><strong>Suggested Use:</strong></p> <p>1 or more capsules per day or as recommended by your health care professional</p>

<span data-mce-fragment="1">Optimal Omegas provides 820 mg of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) as well as 50 mg of docosapentaemoic acid (DPA) per soft gel as re-esterified triglycerides, the preferred form with superior absorption. Vitamin E (as mixed tocopherols) and rosemary extract are used to ensure maximum purity and freshness.</span>

<p>Magnesium is an abundant mineral in the body and is found naturally in many foods, like green leafy vegetables. It is also found in over-the-counter medications, such as laxatives. The average American intake of magnesium, according to the National Health and Nutrition Examination Survey (NHANES Study) is critically low: Many Americans fail to consume the estimated average requirement (EAR) established by the Institute of Medicine. In addition, more than 57% of the population does not meet the United States Department of Agriculture requirements for magnesium in the diet. Intracellular magnesium levels are decreased by excessive intake of alcohol, salt, coffee, phosphoric acid found in sodas, diets high in calcium and high stress levels. Because of widespread nature of magnesium deficiencies, adequate daily intake of magnesium is critical for proper hydration, stress response, muscle relaxation, promoting healthy blood pressure levels, optimal bone mineral density, and blood sugar regulation.</p> <p>Essential Mag provides three unique forms of highly-absorbed magnesium to ensure maximum absorption of this important macromineral. Most magnesium supplements use only a single source of magnesium, which can easily overwhelm a single pathway of absorption and limit uptake. Essential Mag takes advantage of three unique pathways of absorption by providing magnesium as di-magnesium malate, magnesium citrate and magnesium glycinate for enhanced absorption, improved utilization and gastrointestinal (GI) comfort. Some individuals, who take other forms of magnesium supplements, often experience GI side effects, including gas, bloating, diarrhea, constipation or a combination of these symptoms. The forms of magnesium used in Essential Mag preserve GI comfort while maximizing absorption and restoring magnesium levels in the body.</p> <p><strong>Suggested Use:</strong></p> <p>2 or more capsules per day or as recommended by your health care professional</p> <p>Formerly (Reacted Magnesium)</p>

<p><span data-mce-fragment="1">The active components of Ginkgo biloba enhance the flow of oxygen and blood to the brain and promote transmission of nerve impulses, supporting mental acuity. Ginkgo biloba offers nutritional support to the vascular system by sustaining the strength and elasticity of blood vessels and capillaries. This quality product features 120mg of standardized Ginkgo biloba leaf extract 50:1 standardized to 24% flavoneglycosides, 6% terpene lactones and 0.8% ginkgolide B.</span></p> <p><span data-mce-fragment="1">Qty: 50 Capsules</span></p>

<style type="text/css"><!-- td {border: 1px solid #ccc;}br {mso-data-placement:same-cell;} --></style> <span data-sheets-userformat='{"2":771,"3":{"1":0},"4":{"1":3,"3":2},"11":0,"12":0}' data-sheets-value='{"1":2,"2":"Curcumin has a long history of use for maintaining a healthy inflammatory response. It also appears to provide important antioxidant defense. Furthermore, it supports the body’s natural detoxification system and helps maintain healthy hepatic function. Curcumin C3 Complex has been the subject of many clinical studies and is the only turmeric chosen by the National Cancer Institute for clinical studies.\n\nQuantity: 60 Vegetarian Capsules"}'>Curcumin has a long history of use for maintaining a healthy inflammatory response. It also appears to provide important antioxidant defense. Furthermore, it supports the body’s natural detoxification system and helps maintain healthy hepatic function. Curcumin C3 Complex has been the subject of many clinical studies and is the only turmeric chosen by the National Cancer Institute for clinical studies.<br><br>Quantity: 60 Vegetarian Capsules</span>

<style type="text/css"><!-- td {border: 1px solid #ccc;}br {mso-data-placement:same-cell;} --></style> <span data-sheets-userformat='{"2":771,"3":{"1":0},"4":{"1":3,"3":2},"11":0,"12":0}' data-sheets-value='{"1":2,"2":"Co-Enzyme Q10 softgels contain pure co-enzyme Q10 (ubiquinone). Co-enzyme Q10 is solubilized in a base of rice bran oil and vitamin E to enhance absorption of coenzyme Q10.\n\nQuantity: 30 Softgels"}'>Co-Enzyme Q10 softgels contain pure co-enzyme Q10 (ubiquinone). Co-enzyme Q10 is solubilized in a base of rice bran oil and vitamin E to enhance absorption of coenzyme Q10.<br><br>Quantity: 30 Softgels</span>